In her first month playing in Vegas she was $70,000 and moved there permanently. In the 2000 WSOP World Championship Duke finished 10th out of 512 players, while she was almost nine months pregnant. She won a gold bracelet in 2004 and in the same year she won the inaugural WSOP Tournament of Champions and winning $2 million. She won the 2010 NBC National Heads-Up Poker Championship for $500,000. She is the most successful woman to play at the WSOP, with over $1 million in tournament winnings. She has been a spokesperson for ieLogic and Ultimate Bet. She has testified in Congress regarding internet gambling. In 2009 she was a contestant on Celebrity Apprentice where she finished second to Joan Rivers. Duke raised over $700,000 for her charity Refugees International.