He was traded to the Miami Dolphins following a season-ending injury during the 2007 season. While with the Dolphins, Ferguson reclaimed a starting role at nose tackle and put together a solid 2008 and 2009 season before suffering a year-ending knee injury. Heading into the 2010 season, Ferguson was suspended by the league for eight games after failing a league-given drug test. He retired from professional football on July 15, 2010. Ferguson racked up 325 tackles and 21.5 sacks over the course of his career to go along with three forced fumbles in more than 150 games.